Document Detail


Halothane anaesthesia of normal and dystrophic hamsters.
MedLine Citation:
PMID:  1207039     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Induction, carried out in a small clear-plastic box with 3-5% (v/v) halothane in 30:70 (v/v) oxygen: nitrous oxide, was quiet and rapid. Recovery was almost instantaneous. 2% halothane in the oxygen-nitrous oxide mixture was sufficient for maintenance anaesthesia. The anaesthetic mixture was given by face mask in an open circuit specially designed to function at low gas-flow rates. The halothane content of the muscle and blood after 25 min anaesthesia was estimated by gas chromatography of n-heptane extracts. The mean level (+/- s.e.m.) in blood was 22-8 +/- 2-7 mg/100 ml (n=4), and in dystrophic muscle 226 +/- 36-8 mg/100 g wet weight of tissue (n=4): there was a positive correlation (r=0-94) between them (p less than 0-02).
Authors:
J E Carvell; P J Stoward
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Laboratory animals     Volume:  9     ISSN:  0023-6772     ISO Abbreviation:  Lab. Anim.     Publication Date:  1975 Oct 
Date Detail:
Created Date:  1976-03-05     Completed Date:  1976-03-05     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0112725     Medline TA:  Lab Anim     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  345-52     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Anesthesia, Inhalation / instrumentation,  veterinary*
Animals
Body Temperature
Cricetinae*
Female
Halothane* / blood
Male
Muscles / metabolism
Muscular Dystrophy, Animal / metabolism*
Respiration
Rodent Diseases / metabolism*
Chemical
Reg. No./Substance:
151-67-7/Halothane

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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