| Haloperidol-induced neuroleptic malignant syndrome complicated by hyperosmolar hyperglycemic state. | |
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MedLine Citation:
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PMID: 19857430 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Neuroleptic malignant syndrome (NMS) is a life-threatening neurologic emergency that may be caused by neuroleptic agents of any class. The association with hyperosmolar hyperglycemic state (HHS) is rare and carries a grave prognosis. We describe the case of a 25-year-old male patient with haloperidol-induced NMS complicated by HHS that culminated in the patient's death despite all treatment efforts. Physicians caring for diabetic psychiatric patients who are treated with neuroleptic agents should be aware of this association that may be prevented by tight glycemic control. |
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Authors:
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Wasseem Rock; Mazen Elias; Ami Lev; Walid R Saliba |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The American journal of emergency medicine Volume: 27 ISSN: 1532-8171 ISO Abbreviation: Am J Emerg Med Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-10-27 Completed Date: 2009-12-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8309942 Medline TA: Am J Emerg Med Country: United States |
Other Details:
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Languages: eng Pagination: 1018.e1-3 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine C, Ha'emeK Medical Center, Afula, Affiliated to the Technion-Israel Institute of Technology, Faculty of Medicine, Haifa, Israel. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antipsychotic Agents / adverse effects* Fatal Outcome Haloperidol / adverse effects* Humans Hyperglycemia / complications* Male Malignant Hyperthermia / complications, drug therapy Munchausen Syndrome / drug therapy Neuroleptic Malignant Syndrome / complications*, etiology* Schizophrenia / drug therapy |
| Chemical | |
Reg. No./Substance:
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0/Antipsychotic Agents; 52-86-8/Haloperidol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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