| Hair as a novel noninvasive method to study the impact of pregnancy on CYP2D6 metabolizing capacity. | |
| | |
MedLine Citation:
|
PMID: 19701115 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A novel method is described to investigate changes in the drug metabolizing capacity of CYP2D6 during pregnancy using hair analysis. |
| | |
Authors:
|
Lisa O'Brien; Carina Baumer; Detlef Thieme; Hans Sachs; Gideon Koren |
Related Documents
:
|
2401945 - Fetal wound healing: an in vitro explant model. 17147655 - Effect of vibriolysin, an enzymatic debriding agent, on healing of partial-thickness bu... 3705915 - Changes in thickness of collagen fibrils in the endo- and epineurium of the mouse sciat... 1403555 - Biology of fetal wound healing: collagen biosynthesis during dermal repair. 10729075 - Risk factors for stillbirth in holstein heifers under field conditions in france: a pro... 16614625 - The safety of psychotropic drug use during pregnancy: a review. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Therapeutic drug monitoring Volume: 31 ISSN: 1536-3694 ISO Abbreviation: Ther Drug Monit Publication Date: 2009 Oct |
Date Detail:
|
Created Date: 2009-10-16 Completed Date: 2010-01-18 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7909660 Medline TA: Ther Drug Monit Country: United States |
Other Details:
|
Languages: eng Pagination: 531-2 Citation Subset: IM |
Affiliation:
|
Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, Ontario, Canada. lobrien14@gmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Amino Acid Substitution Cytochrome P-450 CYP2D6 / genetics*, metabolism Dose-Response Relationship, Drug Drug Monitoring Female Gene Duplication Genotype Hair / metabolism* Hair Color / genetics* Humans Male Metabolic Clearance Rate / genetics Mutagenesis, Site-Directed Pharmaceutical Preparations Phenotype Pregnancy Pregnancy Complications* Substrate Specificity / genetics |
| Chemical | |
Reg. No./Substance:
|
0/Pharmaceutical Preparations; EC 1.14.14.1/Cytochrome P-450 CYP2D6 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Pharmacokinetic and pharmacodynamic interactions between carbamazepine and aripiprazole in patients ...
Next Document: Physical carboxymethylscleroglucan/calcium ion hydrogels as modified drug delivery systems in topica...