Document Detail


Haemostatic variables and the outcome of myocardial infarction.
MedLine Citation:
PMID:  6198743     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a study of 272 patients with myocardial infarction (MI) the 68 who died within 1 year had significantly higher levels of factor VIIIR:Ag, factor VIII:C, fibrinogen, alpha 1 antitrypsin and alpha 2 macroglobulin than those who survived. The mean white cell count (WCC) and peak creatine kinase (CK) were also significantly higher in those who died compared with the survivors. There was considerable intercorrelation between many of the haemostatic variables, WCC and CK as well as between many of the clinical predictors of outcome and the laboratory variables. The differences in haemostatic variables between those who died and those who survived may merely reflect the size of the infarct; alternatively, the haemostatic system may influence prognosis following an MI.
Authors:
A P Haines; D Howarth; W R North; E Goldenberg; Y Stirling; T W Meade; E B Raftery; M W Millar Craig
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Thrombosis and haemostasis     Volume:  50     ISSN:  0340-6245     ISO Abbreviation:  Thromb. Haemost.     Publication Date:  1983 Dec 
Date Detail:
Created Date:  1984-03-23     Completed Date:  1984-03-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7608063     Medline TA:  Thromb Haemost     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  800-3     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Antigens / analysis
Creatine Kinase / blood
Factor VIII / analysis,  immunology
Female
Fibrinogen / analysis
Hemostasis*
Humans
Leukocyte Count
Male
Middle Aged
Myocardial Infarction / blood*,  mortality
Prognosis
alpha 1-Antitrypsin / analysis
alpha-Macroglobulins / analysis
von Willebrand Factor
Chemical
Reg. No./Substance:
0/Antigens; 0/alpha 1-Antitrypsin; 0/alpha-Macroglobulins; 0/von Willebrand Factor; 9001-27-8/Factor VIII; 9001-32-5/Fibrinogen; EC 2.7.3.2/Creatine Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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