|Haemorrhagic-ischaemic lesions of the neonatal brain: correlation between cerebral visual impairment, neurodevelopmental outcome and MRI in infancy.|
|PMID: 7530219 Owner: NLM Status: MEDLINE|
|The relationship between the degree of cerebral visual impairment, established using the acuity card procedure, and the extent of neurological sequelae was assessed in 65 at-risk neonates in a prospective follow-up study. MRI and CT scans were performed in all infants with severe neurological sequelae. 11 of 12 children with an acuity at or below the 10th centile at 18 months developed cerebral palsy: the underlying condition was extensive cystic leukomalacia in all. An acuity above the 10th centile was no guarantee of normal development, as 10 out of 52 such infants developed cerebral palsy. MRI and CT scans showed that periventricular high signal intensity in the occipital area was a non-specific finding with regard to visual function. Extensive periventricular white matter loss and involvement of the striate/parastriate cortex was found in the most severely visually impaired infants.|
|P Eken; L S de Vries; Y van der Graaf; L C Meiners; O van Nieuwenhuizen|
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|Type: Journal Article; Research Support, Non-U.S. Gov't|
|Title: Developmental medicine and child neurology Volume: 37 ISSN: 0012-1622 ISO Abbreviation: Dev Med Child Neurol Publication Date: 1995 Jan|
|Created Date: 1995-02-21 Completed Date: 1995-02-21 Revised Date: 2009-11-11|
Medline Journal Info:
|Nlm Unique ID: 0006761 Medline TA: Dev Med Child Neurol Country: ENGLAND|
|Languages: eng Pagination: 41-55 Citation Subset: IM|
|Department of Child Neurology, Whilhelmina Children's Hospital, Utrecht, The Netherlands.|
|APA/MLA Format Download EndNote Download BibTex|
Cerebral Hemorrhage / classification, complications*, diagnosis, epidemiology
Developmental Disabilities / epidemiology, etiology*
Leukomalacia, Periventricular / classification, complications*, diagnosis, epidemiology
Magnetic Resonance Imaging*
Severity of Illness Index
Tomography, X-Ray Computed
Ultrasonography, Doppler, Transcranial
Vision Disorders / classification, diagnosis, epidemiology, etiology*
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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