| Haemophilic knee arthropathy: long-term outcome after total knee replacement. | |
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MedLine Citation:
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PMID: 22293897 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: The objective of this study was to evaluate the long-term outcome and prosthetic survival of primary total knee arthroplasty in haemophilic patients. It was hypothesized that the infection and revision rate are higher and the outcome inferior when compared with patients without haemophilia. METHODS: Between 1985 and 2004, forty-three consecutive primary total knee replacements were performed in thirty haemophilic patients. These patients' charts were reviewed retrospectively. Twenty-five patients (34 knees) were available for clinical and radiological follow-up. The outcome was assessed using the Knee Society score, WOMAC and Kaplan-Meier survivorship analysis. RESULTS: An haematogenous infection occurred in two patients. In three patients, component revision was needed: two because of an infection and one because of a mechanical failure. After a mean follow-up of 9.6 years (2-20), 94% of the patients rated their result as either excellent or good. At time of follow-up, the Knee Society Score averaged 73.3 points (range, 29-100) and showed a significant gain (p < 0.001) compared to preoperative. Flexion contracture could be reduced significantly (p < 0.001) from 18.1° preoperatively to 8.4° at follow-up, whereas flexion remained unchanged. When infection or any component replacement was set as endpoints, the 10 years prosthetic survival was 90 and 86%, respectively. CONCLUSION: Total knee arthroplasty in haemophilic patients is a reliable treatment that results in pain relief and functional improvement with a low risk of postoperative infection. However, neither the postoperative infection rate nor the functional result does reach the same level as in a population not affected by haemophilia. LEVEL OF EVIDENCE: IV. |
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Authors:
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Patrick O Zingg; Sandro F Fucentese; Willy Lutz; Brigit Brand; Nadja Mamisch; Peter P Koch |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-2-1 |
Journal Detail:
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Title: Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA Volume: - ISSN: 1433-7347 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-2-1 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9314730 Medline TA: Knee Surg Sports Traumatol Arthrosc Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Division of Knee Surgery, Department of Orthopaedics, University of Zurich Balgrist, Forchstrasse 340, 8008, Zürich, Switzerland. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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