Document Detail


Haemolytic-uraemic syndrome treated with heparin.
MedLine Citation:
PMID:  5448778     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Three children with the haemolytic-uraemic syndrome were treated with intravenous heparin. Peritoneal dialysis was required for two of them, one of whom died after 26 days of therapy. Renal biopsy specimens from the two survivors showed widespread glomerular disease, which appeared permanent in one case, but only occasional thrombi. It is suggested that heparin therapy, by preventing further intrarenal thrombosis, allowed the normal fibrinolytic mechanisms to remove previously formed thrombi.
Authors:
M W Moncrieff; E F Glasgow
Related Documents :
7205438 - Nephron injury in the haemolytic-uraemic syndrome complicating bacillary dysentery.
6373838 - Necrosis of the pancreas in the haemolytic uraemic syndrome.
23402998 - Distinct renal pathology and a chemotactic phenotype after enterohemorrhagic escherichi...
24014798 - Loeys-dietz syndrome with bilateral radial head dislocations: a case report.
20007548 - Trisomy of erg is required for myeloproliferation in a mouse model of down syndrome.
11535008 - Levodopa responsive parkinsonism in adults with angelman syndrome.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  3     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1970 Jul 
Date Detail:
Created Date:  1970-09-28     Completed Date:  1970-09-28     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  188-91     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Anemia, Hemolytic / drug therapy*,  pathology
Child
Female
Heparin / administration & dosage,  therapeutic use*
Humans
Infant
Injections, Intravenous
Kidney / pathology
Kidney Cortex Necrosis / drug therapy,  pathology
Kidney Failure, Acute / drug therapy*,  pathology,  therapy
Kidney Glomerulus / pathology
Male
Peritoneal Dialysis
Thrombocytopenia / drug therapy,  pathology
Chemical
Reg. No./Substance:
9005-49-6/Heparin
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Host resistance and survival in carcinoma of breast: a study of 104 cases of medullary carcinoma in ...
Next Document:  Failure of a pure progestogen contraceptive to affect serum levels of iron, transferrin, protein-bou...