| Haemolytic-uraemic syndrome during severe lupus nephritis: efficacy of plasma exchange. | |
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MedLine Citation:
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PMID: 22276560 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Systemic lupus erythematosus (SLE) has been described as a cause of thrombotic microangiopathy, especially thrombotic thrombocytopenic purpura (TTP). Haemolytic-uraemic syndrome (HUS) is less frequent in SLE. We report a case of such an association during an episode of severe lupus nephritis in a young woman, who was successfully treated with steroids, cyclophosphamide and especially plasma exchange with plasma replacement. This report highlights the importance of recognising atypical HUS in SLE patients by looking for schistocytes in case of haemolytic anemia with a negative antiglobulin test, in order to begin plasma exchange. |
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Authors:
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M Samson; S Audia; V Leguy; S Berthier; N Janikashvili; L Martin; B Bonnotte; B Lorcerie |
Publication Detail:
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Type: Letter |
Journal Detail:
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Title: Internal medicine journal Volume: 42 ISSN: 1445-5994 ISO Abbreviation: Intern Med J Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-01-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101092952 Medline TA: Intern Med J Country: Australia |
Other Details:
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Languages: eng Pagination: 95-8 Citation Subset: IM |
Copyright Information:
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© 2012 The Authors. Internal Medicine Journal © 2012 Royal Australasian College of Physicians. |
Affiliation:
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Department of Internal Medicine and Clinical Immunology Laboratory of Pathology and Cytology, Dijon University Hospital, Dijon, France Faculty of Medicine and Pharmacy, CR INSERM 866, Lipids Nutrition Cancer, University of Burgundy, Dijon, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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