Document Detail


Haemolytic crisis in sheep as a result of chronic exposure to copper.
MedLine Citation:
PMID:  17388026     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Usually practicing veterinarians and animal keepers have to deal with inadequate supplementation of copper which causes deficiency diseases. However, instead of curing, the consequential intake of copper is likely to cause copper intoxication. Copper poisoning is observed particularly frequently, in sheep--the most sensitive domestic animal to copper toxicity. In most cases, sheep undergo chronic exposure to copper causing liver necrosis and resulting in massive haemolysis, haemoglobinuria and eventually in renal failure. The observed symptoms have an acute character and a set of them is called haemolytic crisis. The pathogenesis, signs and diagnosis of this syndrome are described in this article.
Authors:
M Mendel; M Chłopecka; N Dziekan
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Polish journal of veterinary sciences     Volume:  10     ISSN:  1505-1773     ISO Abbreviation:  Pol J Vet Sci     Publication Date:  2007  
Date Detail:
Created Date:  2007-03-28     Completed Date:  2007-05-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101125473     Medline TA:  Pol J Vet Sci     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  51-6     Citation Subset:  IM    
Affiliation:
Division of Pharmacology and Toxicology, Department of Preclinical Sciences, Faculty of Veterinary Medicine, Warsaw Agricultural University, Ciszewskiego 8, 02-786 Warszawa, Poland. martamendel@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Copper / administration & dosage*,  adverse effects*
Dietary Supplements*
Drug Administration Schedule / veterinary*
Hemolysis / drug effects*
Sheep
Sheep Diseases / chemically induced*
Chemical
Reg. No./Substance:
7440-50-8/Copper

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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