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Haemolytic Complement Activity of Sera of Foetal and New-Born Lambs.
MedLine Citation:
PMID:  17649488     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Determination of the haemolytic complement titres of serum from 24 foetal lambs bled at 77 to 149 days gestation failed to reveal this activity earlier than 123 days. Titres near the end of the gestation period of 150 days were still very low. Among serum specimens collected from 17 newborn lambs before suckling, three were still without demonstrable complement activity. During the first week titres rose considerably in all of these lambs, were higher at three weeks but at ten weeks were still below the adult level.A number of foeti had been injected with antigen mixtures at 50 to 111 days' gestation and had responded with antibody development to one or more of these antigens. The rate of development of complement in these treated foetal lambs appeared similar to that in their untreated twin controls.
Authors:
C E Rice; A M Silverstein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian journal of comparative medicine and veterinary science     Volume:  28     ISSN:  0316-5957     ISO Abbreviation:  Can J Comp Med Vet Sci     Publication Date:  1964 Feb 
Date Detail:
Created Date:  2007-07-27     Completed Date:  2007-07-27     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0151757     Medline TA:  Can J Comp Med Vet Sci     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  34-7     Citation Subset:  -    
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