Document Detail


[Haemoglobin oxygenation of retinal vessels in branch retinal artery occlusions over time and correlation with clinical outcome].
MedLine Citation:
PMID:  20349400     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: Purpose of these study was the evaluation of a new method for the measurement of haemoglobin oxygenation in retinal vessels. Patients with branch retinal artery occlusion have been measured before and after a rheological therapy.
METHODS: The haemoglobin oxygenation in retinal vessels was measured by the "oxygen module" (Imedos GmbH, Jena, Germany) which uses a special filter (transmission at 548 and 610 nm, band width 10 nm) in the illumination path of a fundus camera. Fundus images were acquired by a colour CCD camera and specific software was used for vessel tracking and calculation of their haemoglobin oxygen saturation. 11 patients with branch retinal artery occlusions, average age 63.4 ± 11.7 years were investigated at time of diagnosis and at the 5th day of a rheological and intraocular pressure reduction therapy.
RESULTS: 10 out of 11 patients have shown an increase of haemoglobin oxygenation over time (on average from 73 ± 16 % to 87 ± 11 %). This increase was statistically significant (p < 0.05, Wilcoxon test). Non-affected retinal areas have also shown an increase of haemoglobin oxygenation. The visual acuity improved by one line. This increase in visual acuity was, however, not statistically significant.
CONCLUSIONS: We observed an increase of the arterial haemoglobin oxygenation. One possible reason of the improvement of the haemoglobin oxygenation by the therapy may be an increase of the rheological properties of the blood. All patients showed an increase or at least a stabilisation of their visual acuity. Retinal vessel oximetry might be used as an additional parameter in the follow-up of retinal artery occlusion.
Authors:
S Gehlert; J Dawczynski; M Hammer; J Strobel
Publication Detail:
Type:  English Abstract; Journal Article     Date:  2010-03-26
Journal Detail:
Title:  Klinische Monatsblätter für Augenheilkunde     Volume:  227     ISSN:  1439-3999     ISO Abbreviation:  Klin Monbl Augenheilkd     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0014133     Medline TA:  Klin Monbl Augenheilkd     Country:  Germany    
Other Details:
Languages:  ger     Pagination:  976-80     Citation Subset:  IM    
Copyright Information:
© Georg Thieme Verlag KG Stuttgart · New York.
Affiliation:
Klinik für Augenheilkunde, Universitätsklinikum Jena, Jena. simone.gehlert@med.uni-jena.de
Vernacular Title:
Nichtinvasive Messung der Sauerstoffsättigung retinaler Gefäße bei retinalen Astarterienverschlüssen unter Therapie.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Photodynamic Therapy with Verteporfin in Occult Choroidal Neovascularization in Age-Related Macular ...
Next Document:  Recall and bias of retrieving gene expression microarray datasets through PubMed identifiers.