| Haemodynamic model of a unilateral iliac stenosis with an aortoiliac bypass. | |
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MedLine Citation:
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PMID: 8145580 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A hydrodynamic model for the part of the human arterial network below the renal arteries has been constructed using specially fabricated distensible tubes and a pulsatile pump to simulate an aortoiliac bypass. The experiments and the computer model indicated that no 'steal' occurred due to the insertion of the bypass graft. Also, the results showed that the length of the stenosis had a non-systematic apparent effect on the physiological significance of the obstruction and that the kinetic power represented only a small percentage of the total power. The total power efficiency of the bypass graft was unaffected by its elastic properties. The experimental investigation also indicated that the pressure drop across the stenosis was considerably larger than the drop calculated using the Poiseuille flow relationship when the stenosis was severe. Therefore, a critical arterial stenosis value cannot be defined as an obstruction of a constant percentage reduction of luminal area. It varies directly with the effective cross-sectional area and inversely with the flow rate. The value of angiography in assessing the functional significance of any arterial stenosis is therefore limited. A better method for evaluation requires quantitative measurements of local blood pressure and blood flow, not only at rest, but also under conditions creating augmented flows due to exercise. |
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Authors:
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M A Helal; K C Watts; A E Marble |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Medical & biological engineering & computing Volume: 31 ISSN: 0140-0118 ISO Abbreviation: Med Biol Eng Comput Publication Date: 1993 Nov |
Date Detail:
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Created Date: 1994-05-04 Completed Date: 1994-05-04 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7704869 Medline TA: Med Biol Eng Comput Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 562-8 Citation Subset: IM |
Affiliation:
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Department of Design and Study, Ministry of Health, Riyadh, Kingdom of Saudi Arabia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aorta
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surgery* Arterial Occlusive Diseases / physiopathology*, surgery Blood Vessel Prosthesis* Hemodynamics Humans Iliac Artery / surgery* Mathematics Models, Cardiovascular* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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