Document Detail

Haemodynamic limitations and exercise performance in peripheral arterial disease.
MedLine Citation:
PMID:  12005160     Owner:  NLM     Status:  MEDLINE    
It has been frequently argued that haemodynamic limitations are poor predictors of exercise performance in people with peripheral arterial disease (PAD) and intermittent claudication. This review has tried to address this argument through a review of published data that appears to support or counterbalance it, brief consideration of some of the methodological limitations associated with these data, as well as some other considerations. The main argument rests primarily upon data about the resting ankle-brachial index (ABI) and/or blood flow after calf exercise or an ischaemic challenge; whereas the counter argument rests mainly on data about blood flow during walking or cyding exercise. Consideration of the limitations of all methods suggests that the measurement of blood flow during exercise has the greatest value in explaining differences in exercise performance amongst claudicants; whereas the other methods are relatively limited in their explanatory value. This strengthens the counter argument and undermines the main argument proposed by others. Consequently, asserting that haemodynamic limitations are poor predictors of exercise performance in claudicants is not justified in light of available evidence.
S Green
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical physiology and functional imaging     Volume:  22     ISSN:  1475-0961     ISO Abbreviation:  Clin Physiol Funct Imaging     Publication Date:  2002 Mar 
Date Detail:
Created Date:  2002-05-13     Completed Date:  2002-06-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  101137604     Medline TA:  Clin Physiol Funct Imaging     Country:  England    
Other Details:
Languages:  eng     Pagination:  81-91     Citation Subset:  IM    
Deportment of Physiology, Trinity College, University of Dublin, Ireland.
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MeSH Terms
Exercise Test
Hyperemia / diagnosis,  physiopathology
Intermittent Claudication / diagnosis*,  physiopathology*
Peripheral Vascular Diseases / diagnosis*,  physiopathology*
Predictive Value of Tests
Regional Blood Flow

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