Document Detail

Haemodynamic and electroencephalographic response to insertion of a cuffed oropharyngeal airway: comparison with the laryngeal mask airway.
MedLine Citation:
PMID:  9861128     Owner:  NLM     Status:  MEDLINE    
We have compared the cuffed oropharyngeal airway (COPA), a modified Guedel airway device with a specially designed cuff at its distal end, with the laryngeal mask airway (LMA), on haemodynamic and electroencephalographic (EEG) responses to insertion. In addition, we examined the haemodynamic and EEG changes during initiation of the effect-compartment controlled infusion. We studied 35 female patients undergoing ambulatory gynaecological surgery allocated randomly to received an LMA or COPA to manage the airway. After premedication with midazolam 0.03 mg kg-1 i.v. and low-dose alfentanil (0.01 mg kg-1), anaesthesia was induced and maintained with propofol, using an effect-compartment controlled infusion set at an effect-site concentration of 4 micrograms ml-1. After intercompartmental equilibration, the LMA (group I) or COPA (group II) was inserted and haemodynamic (arterial pressure, heart rate) and EEG (bispectral index (BIS)) responses to insertion studied. The effect-compartment controlled infusion of propofol caused only mild haemodynamic changes during induction. Changes in arterial pressure and heart rate after insertion were similar in both groups and not significantly different from baseline values before insertion. Changes in BIS after insertion were minor and similar between groups.
L Versichelen; M Struys; E Crombez; K Fonck; E Mortier; G Rolly
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  British journal of anaesthesia     Volume:  81     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1999-01-04     Completed Date:  1999-01-04     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  393-7     Citation Subset:  IM    
Department of Anaesthesia, University Hospital of Gent, Belgium.
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MeSH Terms
Ambulatory Surgical Procedures
Analysis of Variance
Blood Pressure
Gynecologic Surgical Procedures
Heart Rate
Intubation, Intratracheal / instrumentation*
Laryngeal Masks
Monitoring, Intraoperative

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