| Haematological and hormonal responses to dynamic exercise in patients with chronic airway obstruction. | |
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MedLine Citation:
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PMID: 3032646 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The influence of exercise on hormonal and total white blood cells (WBC), lymphocytes (L). Granulocytes (GR), and platelet (P) count responses was studied in: twenty-five patients with chronic airway obstruction (CAO, 47 +/- 1.8 years, mean +/- SEM) and thirteen normal subjects (N, 36 +/- 2.6 years). They performed a submaximal (40 W) and a maximal exercise (VO2max). Arterial blood samples were taken at rest, 40 W, and VO2max. [H+], PaCO2, PaO2 haematocrit (Hct), [Hb], P, total platelet volume (TPV), WBC, GR, L, and total red blood cells (RBC) were measured. At rest, WBC, GR, P and TPV were higher in CAO patients, whilst PaO2 and cortisol were lower. At 40 W, when compared to values obtained at rest, WBC, GR, L, P and TPV were increased in both groups; WBC, GR, P and TPV were higher in CAO patients. VO2max of CAO patients represented 54% of that of controls. At VO2max, Hct, [Hb] and RBC were approximately 10% higher than at rest in both groups, whilst changes were more significant in normals for WBC (CAO = 55%, N = 76%), lymphocytes (CAO = 83%, N = 105%), GR, (CAO = 37%; N = 51%), platelets (CAO = 23%, N = 29%), TPV (CAO = 25.4%, N = 35%), [H+] (CAO = 43%, N = 38%) and ACTH (CAO = 82%, N = 139%). PaO2 and cortisol did not differ between groups. PaCO2 and platelets however, were higher in the CAO group.(ABSTRACT TRUNCATED AT 250 WORDS) |
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Authors:
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M Gimenez; T Mohan-Kumar; J C Humbert; N de Talance; M Teboul; J L Ponz; J M Polu |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of clinical investigation Volume: 17 ISSN: 0014-2972 ISO Abbreviation: Eur. J. Clin. Invest. Publication Date: 1987 Feb |
Date Detail:
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Created Date: 1987-06-22 Completed Date: 1987-06-22 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0245331 Medline TA: Eur J Clin Invest Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 75-80 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenocorticotropic Hormone
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blood* Adult Blood Cell Count* Blood Gas Analysis Bronchitis / blood* Chronic Disease Granulocytes Hematocrit Hemoglobins / metabolism Humans Hydrocortisone / blood* Leukocyte Count Lymphocytes Male Physical Exertion* Platelet Count |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins; 50-23-7/Hydrocortisone; 9002-60-2/Adrenocorticotropic Hormone |
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