Document Detail


Haematological changes and iron status in teenage girls with eating disorders and weight loss-the importance of menstrual status.
MedLine Citation:
PMID:  17326759     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To study haematological changes and iron stores in teenage girls with eating disorders and weight loss. METHODS: Blood haemoglobin concentration, white blood cell and thrombocyte count and serum ferritin concentration were measured at assessments of 446 subjects. RESULTS: Haemoglobin concentrations, leukocyte and thrombocyte counts were related to weight and rate of weight loss but were largely within reference ranges. Serum ferritin concentrations were high in girls with amenorrhea and related to weight and rate of weight loss. Girls who retained menstruations had low serum ferritin concentrations and 37% had depleted iron stores (serum ferritin<16 microg/L). CONCLUSION: Anaemia, leukopenia and thrombocytopenia are uncommon in teenage girls with eating disorders and weight loss. When present, other diseases causing haematological changes should be considered. In amenorrhoic girls muscle catabolism increases serum ferritin concentrations which may give a false impression of an adequate iron status. This is unmasked in girls with retained menstruations who often have depleted iron stores.
Authors:
Ingemar Swenne
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-02-26
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  96     ISSN:  0803-5253     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-29     Completed Date:  2007-05-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  530-3     Citation Subset:  IM    
Affiliation:
Department of Women's and Children's Health, Uppsala University Children's Hospital, Uppsala, Sweden. ingemar.swenne@akademiska.se
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Amenorrhea / blood,  etiology
Eating Disorders / blood*,  complications
Female
Ferritins / blood*
Hemoglobins / metabolism*
Humans
Leukocyte Count
Menstruation / blood
Platelet Count
Retrospective Studies
Weight Loss / physiology*
Chemical
Reg. No./Substance:
0/Hemoglobins; 9007-73-2/Ferritins

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