Document Detail


The HUPO Brain Proteome Project--no need to hurry?
MedLine Citation:
PMID:  16835694     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The HUPO Brain Proteome Project (HUPO BPP) is dedicated to the analysis of the brain proteome and has initiated two pilot studies in order to elaborate a standardised system for data collection and reprocessing. Samples of mouse brains (different developmental stages) and human brain tissue (biopsy and post-mortem samples) were shipped to different laboratories in Europe, Asia and the US that were invited to identify as many proteins as possible using their own approaches. In addition, a centralised data reprocessing strategy has been elaborated in an iterative way to generate highly reliable lists of identified proteins. This consortium could be a good example for a standardized proteomics workflow.
Authors:
M Hamacher; K Marcus; A van Hall; H E Meyer; C Stephan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2006-07-13
Journal Detail:
Title:  Journal of neural transmission (Vienna, Austria : 1996)     Volume:  113     ISSN:  0300-9564     ISO Abbreviation:  J Neural Transm     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-19     Completed Date:  2007-02-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9702341     Medline TA:  J Neural Transm     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  963-71     Citation Subset:  IM    
Affiliation:
Medical Proteom-Center, Ruhr-Universität Bochum, Bochum, Germany. michael.hamacher@rub.de
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MeSH Terms
Descriptor/Qualifier:
Animals
Brain Chemistry*
Databases, Protein*
Humans
International Cooperation*
Proteomics / organization & administration*

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