Document Detail

HTLV-I-associated lymphoma presenting as mycosis fungoides in an HTLV-I non-endemic area: a viro-molecular study.
MedLine Citation:
PMID:  7662579     Owner:  NLM     Status:  MEDLINE    
Human T-lymphotropic virus type I (HTLV-I) is endemic in the Caribbean region, south-western Japan and Africa, and is associated with tropical spastic paraparesis and adult T-cell leukaemia/lymphoma (ATLL). Cutaneous forms of ATLL are sometimes indistinguishable from other cutaneous T-cell lymphomas (CTCL). We report a woman living in a non-endemic area for HTLV-I, with no risk factors for viral infection, who developed mycosis fungoides-like ATLL. The findings underline the usefulness of molecular biological techniques in distinguishing between mycosis fungoides and ATLL. We emphasize the need to establish the HTLV-I status of patients with CTCL, even in HTLV-I non-endemic areas, not only to establish a preventive policy in these countries, but also to further our knowledge of the lymphoproliferation spectrum associated with human retroviruses.
M D'Incan; O Antoniotti; M Gasmi; Y Fonck; J Chassagne; C Desgranges; P Souteyrand
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The British journal of dermatology     Volume:  132     ISSN:  0007-0963     ISO Abbreviation:  Br. J. Dermatol.     Publication Date:  1995 Jun 
Date Detail:
Created Date:  1995-10-10     Completed Date:  1995-10-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0004041     Medline TA:  Br J Dermatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  983-8     Citation Subset:  IM; X    
Laboratory of Research on Hepatitis, AIDS and Human Retroviruses, INSERM U 271, Lyon, France.
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MeSH Terms
Antibodies, Viral / blood
Blotting, Southern
DNA, Viral / analysis
Diagnosis, Differential
Human T-lymphotropic virus 1* / genetics,  immunology
Leukemia-Lymphoma, Adult T-Cell / diagnosis*
Mycosis Fungoides / diagnosis*
Skin Neoplasms / diagnosis*
Reg. No./Substance:
0/Antibodies, Viral; 0/DNA, Viral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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