Document Detail


HTLV-1 sequences in lymphocytes of a patient with non-tropical spastic tetraparesis and her asymptomatic husband.
MedLine Citation:
PMID:  8469167     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe a 65-year-old woman born and living in Northern Italy affected by non tropical spastic tetraparesis and her asymptomatic husband presenting HTLV-1 sequences in their lymphocytes detected by polymerase chain reaction (PCR). We discuss the significance of the case and the mechanism involved in HTLV-1 infection and the relationship with neurological disorders, stressing that this case is the first reported in Italy.
Authors:
N Manca; M Gelmi; F Mattioli; F Gargiulo; L Terlenghi; F Pirali; A Turano
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The new microbiologica     Volume:  16     ISSN:  1121-7138     ISO Abbreviation:  New Microbiol.     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-05-11     Completed Date:  1993-05-11     Revised Date:  2011-02-25    
Medline Journal Info:
Nlm Unique ID:  9516291     Medline TA:  New Microbiol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  11-7     Citation Subset:  IM; X    
Affiliation:
Institute of Microbiology, University of Brescia, Italy.
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MeSH Terms
Descriptor/Qualifier:
Blotting, Southern
Blotting, Western
Cells, Cultured
DNA Probes / diagnostic use
DNA, Viral / blood,  isolation & purification
Enzyme-Linked Immunosorbent Assay
Female
Genes, env
Genes, pX
Genes, pol
HTLV-I Antibodies / blood
HTLV-I Antigens / blood
HTLV-I Infections / diagnosis,  microbiology*
Human T-lymphotropic virus 1 / genetics,  immunology,  isolation & purification*
Humans
Lymphocytes / microbiology*
Male
Middle Aged
Paralysis / diagnosis,  microbiology*
Polymerase Chain Reaction
Chemical
Reg. No./Substance:
0/DNA Probes; 0/DNA, Viral; 0/HTLV-I Antibodies; 0/HTLV-I Antigens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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