Document Detail

The HOPE Registry: first US registry for oocyte cryopreservation.
MedLine Citation:
PMID:  19079955     Owner:  NLM     Status:  MEDLINE    
The Human Oocyte Preservation Experience (HOPE) Registry is an initiative of EMD Serono which aims to systematically track the outcomes of oocyte cryopreservation cycles and validate the efficacy and safety of techniques to freeze and thaw oocytes. Beginning in November 2008 (ASRM, San Francisco, CA), the registry will be performed as a national Phase IV observational 5-year study (including 3 years of enrolment and 2 years follow-up of babies born) in the USA and will enrol approximately 400 women of reproductive age who have thawed frozen oocytes for subsequent use through in-vitro fertilization (IVF) and embryo transfer (ET). Data relating to controlled ovarian stimulation protocols, freezing and thawing of oocytes, culture and transfer of resulting embryos, implantation rates, pregnancy outcomes and information on child health and development after birth and at 12 months will be recorded. It is anticipated that the HOPE Registry will provide answers to various unresolved questions from healthcare providers and their patients who use oocyte cryopreservation to preserve fertility, such as oocyte cryopreservation and thawing techniques and other factors associated with successful cycle outcomes.
Diego Ezcurra; Jennifer Rangnow; Maryellen Craig; Joan Schertz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  17     ISSN:  1472-6491     ISO Abbreviation:  Reprod. Biomed. Online     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-12-16     Completed Date:  2009-04-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  England    
Other Details:
Languages:  eng     Pagination:  743-4     Citation Subset:  IM    
EMD Serono Inc., Rockland, MA, USA.
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MeSH Terms
Cryopreservation / methods*
Embryo Transfer
Fertilization in Vitro
Oocytes / cytology,  metabolism,  physiology*
Ovulation Induction
Reproductive Techniques, Assisted / trends
Treatment Outcome
United States

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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