Document Detail


HLA typing in patients with multiple evanescent white dot syndrome (MEWDS).
MedLine Citation:
PMID:  9798192     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Multiple evanescent white dot syndrome (MEWDS) is an acquired chorioretinal disorder of unknown etiology. We investigated the possibility that MEWDS might be related to a specific HLA subtyping.
METHODS/RESULTS: Blood was obtained from nine patients affected by MEWDS. HLA-B51 was found in four of these nine patients with MEWDS.
CONCLUSION: There was a 3.7-fold increased frequency of HLA-B51 in patients affected by MEWDS (relative risk 5.86). MEWDS might then be related to the presence of a specific HLA subtype, HLA-B51. However, due to the small sample size, our results need to be confirmed by further testing.
Authors:
F X Borruat; C P Herbort; F Spertini; A B Desarnaulds
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ocular immunology and inflammation     Volume:  6     ISSN:  0927-3948     ISO Abbreviation:  Ocul. Immunol. Inflamm.     Publication Date:  1998 Mar 
Date Detail:
Created Date:  1999-01-29     Completed Date:  1999-01-29     Revised Date:  2010-11-29    
Medline Journal Info:
Nlm Unique ID:  9312169     Medline TA:  Ocul Immunol Inflamm     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  39-41     Citation Subset:  IM    
Affiliation:
Hôpital Ophtalmique Jules Gonin, Lausanne, Switzerland.
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MeSH Terms
Descriptor/Qualifier:
HLA Antigens / classification*
HLA-B Antigens / analysis
Humans
Reference Values
Retina / pathology
Retinal Diseases / immunology*,  pathology
Syndrome
Vision Disorders / immunology*
Chemical
Reg. No./Substance:
0/HLA Antigens; 0/HLA-B Antigens; 0/HLA-B51

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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