| HLA and rheumatic fever in Turkish Children. | |
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MedLine Citation:
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PMID: 1518738 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report the results of research on human leukocyte allo-antigen (HLA) and rheumatic fever (RF), the first published study to be carried out among Turkish children with RF. Ninety-three Turkish children, aged between 6 and 16 years (mean: 8 +/- 2.6), with RF participated in the study. Of the total, 26 patients had their first attack and 39 had acute rheumatic activity at the time of registration. The results demonstrate (1) negative but not significant association between HLA-A2 and RF; (2) a positive association between HLA-DR4 and RF (p less than 0.001); (3) a significant association between HLA-DR4 and carditis, but not with isolated arthritis. These results corroborate the concept of race-specific genetically determined familial susceptibility to the development of rheumatic heart disease. |
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Authors:
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H E Khosroshahi; O Kahramanyol; L Doğanci |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pediatric cardiology Volume: 13 ISSN: 0172-0643 ISO Abbreviation: Pediatr Cardiol Publication Date: 1992 Oct |
Date Detail:
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Created Date: 1992-10-07 Completed Date: 1992-10-07 Revised Date: 2008-02-20 |
Medline Journal Info:
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Nlm Unique ID: 8003849 Medline TA: Pediatr Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 204-7 Citation Subset: IM |
Affiliation:
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Division of Pediatric Cardiology, Social Security Children's Hospital, Dişkapi, Ankara, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Child Female HLA-DR Antigens / analysis* Humans Male Rheumatic Fever / genetics*, immunology Turkey |
| Chemical | |
Reg. No./Substance:
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0/HLA-DR Antigens |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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