Document Detail


HLA and childhood asthma (author's transl)
MedLine Citation:
PMID:  7307645     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to study the relationship between human leukocyte antigens (HLA) and the occurrence of childhood bronchial asthma in Chinese, HLA typings were done, by using commercially available HLA immunoplates (Behring, West Germany), in 99 children with allergic bronchial asthma who attended the allergy clinic of the Department of Pediatrics, National Taiwan University Hospital and had been receiving hyposensitization. The results showed: (1) There was no difference in the frequency of HL-A antigens between patients and normals, (2) while HLA-B5 appeared more frequently in patients than in normals (relative risk 2.28-3.18, chi 2 = 15.39, p less than 0.001), HLA-B17 was less often seen in patients than in normals (relative risk 0.19, chi 2 = 33.49 p less than 0.001). It is, therefore, concluded that in Chinese, individuals carrying HLA-B5 have higher chance to be affected by bronchial asthma and those carrying HLA-B17 are less likely to become asthmatics in their childhood.
Authors:
L S Huang; K H Hsieh; S Y Liu
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology     Volume:  14     ISSN:  0253-2662     ISO Abbreviation:  Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi     Publication Date:  1981 Jun 
Date Detail:
Created Date:  1982-02-22     Completed Date:  1982-02-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8008067     Medline TA:  Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi     Country:  TAIWAN    
Other Details:
Languages:  chi     Pagination:  102-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Asthma / immunology*
Child
Child, Preschool
Female
HLA Antigens / analysis*
Humans
Male
Chemical
Reg. No./Substance:
0/HLA Antigens

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