Document Detail

HLA antigens and primary open-angle glaucoma in black Americans.
MedLine Citation:
PMID:  832979     Owner:  NLM     Status:  MEDLINE    
Black patients with primary open-angle glaucoma, when compared to nonglaucomatous individuals, demonstrate significantly increased prevalences of the HLA antigens B7 and B12 and significantly decreased frequencies of A1 and A11. White patients with primary open-angle glaucoma have in common with blacks the increases in B7 and B12 and the decrease in A11, but present no deficit of A1. In addition, white patients with primary open-angle glaucoma demonstrate a significant increase of A3 and a decrease of Bw35, both of which are not found in blacks.
B Becker; D H Shin
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  16     ISSN:  0146-0404     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  1977 Feb 
Date Detail:
Created Date:  1977-03-31     Completed Date:  1977-03-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  175-6     Citation Subset:  IM    
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MeSH Terms
African Continental Ancestry Group*
Glaucoma / genetics,  immunology*
HLA Antigens*
Histocompatibility Antigens*
Reg. No./Substance:
0/HLA Antigens; 0/Histocompatibility Antigens

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