Document Detail


HLA antigens in relationship to duodenal ulceration, gastric acid secretion and the clinical result following vagotomy.
MedLine Citation:
PMID:  6977396     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The distribution of 20 HLA antigens was measured in 100 patients with a duodenal ulcer. An increase (P less than 0.05) in the incidence of the HLA-BW35 antigen was identified which conferred an increased risk factor of developing a duodenal ulcer of 2.7. The preoperative acid output in patients who had the BW35 antigen was significantly lower than that found in all other patients prior to surgery. The clinical outcome from definitive surgical treatment did not appear to be influenced by the HLA status of the patients.
Authors:
M J Gough; S M Rajah; G R Giles
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The British journal of surgery     Volume:  69     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  1982 Feb 
Date Detail:
Created Date:  1982-05-21     Completed Date:  1982-05-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  105-7     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Duodenal Ulcer / immunology*,  surgery
Female
Gastric Acid / metabolism*
HLA Antigens / analysis*
HLA-B Antigens
HLA-B35 Antigen
Humans
Male
Middle Aged
Postoperative Period
Risk
Vagotomy
Chemical
Reg. No./Substance:
0/HLA Antigens; 0/HLA-B Antigens; 0/HLA-B35 Antigen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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