Document Detail


HLA antigens in Alzheimer's disease.
MedLine Citation:
PMID:  7466786     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The histocompatibility antigens of the A, B and C loci were typed for 32 patients with Alzheimer's disease and 35 controls of the same age. The results were also compared to the distribution of HLA antigens in a series of 900 healthy blood donors. No statistically significant differences were found between the Alzheimer patients and the controls. HLA--Cw1 was found significantly less frequently in the group comprising the patients with Alzheimer's disease and their controls together, than in the younger blood group. This leads us to suggest that an age-matched control group may be needed, at least when the patients are elderly.
Authors:
R Sulkava; S Koskimies; J Wikström; J Palo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Tissue antigens     Volume:  16     ISSN:  0001-2815     ISO Abbreviation:  Tissue Antigens     Publication Date:  1980 Aug 
Date Detail:
Created Date:  1981-04-21     Completed Date:  1981-04-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0331072     Medline TA:  Tissue Antigens     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  191-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Alzheimer Disease / immunology*
Dementia / immunology*
Female
HLA Antigens / analysis*
Humans
Male
Middle Aged
Chemical
Reg. No./Substance:
0/HLA Antigens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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