| HLA and Japanese MS. | |
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MedLine Citation:
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PMID: 80838 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Determination of HLA-A, -B and -C types in 43 Japanese patients with multiple sclerosis (MS) and of DR type in 25 MS patients was carried out using antisera from the 7th International Histocompatibility Workshop. The results were compared with 46 controls typed simultaneously. Twenty-three patients were also tested for HLA-Dw2. The conclusions were: 1) There were no significantly higher occurrences of HLA-A3, B7, Dw2 or DRw2 in Japanese MS. 2) Japanese MS might nevertheless be associated with the human major histocompatibility complex, because HLA-B40 was significantly less frequent in MS and two anti HLA-DRw sera, 7w008 and 034, reacted positively more often against lymphocytes from MS patients. |
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Authors:
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S Naito; Y Kuroiwa; T Itoyama; T Tsubaki; A Horikawa; T Sasazuki; S Noguchi; S Ohtsuki; H Tokuomi; T Miyatake; N Takahata; S Kawanami |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Tissue antigens Volume: 12 ISSN: 0001-2815 ISO Abbreviation: Tissue Antigens Publication Date: 1978 Jul |
Date Detail:
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Created Date: 1978-11-22 Completed Date: 1978-11-22 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0331072 Medline TA: Tissue Antigens Country: DENMARK |
Other Details:
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Languages: eng Pagination: 19-24 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Epitopes Gene Frequency HLA Antigens* / analysis Humans Japan Lymphocytes / immunology Major Histocompatibility Complex Multiple Sclerosis / genetics* Phenotype |
| Chemical | |
Reg. No./Substance:
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0/Epitopes; 0/HLA Antigens |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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