Document Detail


HLA-DPB1 polymorphism in seven South American Indian tribes in Colombia.
MedLine Citation:
PMID:  8803536     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
HLA-DPB1 allele frequencies were investigated in seven geographically and linguistically distinct Amerindian tribes of Colombia. Allele *1301 was found only in the Embera tribe living along the Pacific coast, while allele *0101 was found only in two individuals of the Wayuu tribe inhabiting the Guajira desert. Significant geographical variation was observed in the other two alleles (*1401 and *0402), which were found in all seven tribal groups. The possible reasons for this restricted polymorphism and the genetic diversity found in the investigation are discussed.
Authors:
I Briceno; A Gomez; J E Bernal; S S Papiha
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics     Volume:  23     ISSN:  0960-7420     ISO Abbreviation:  Eur. J. Immunogenet.     Publication Date:  1996 Jun 
Date Detail:
Created Date:  1996-12-04     Completed Date:  1996-12-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9106962     Medline TA:  Eur J Immunogenet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  235-40     Citation Subset:  IM    
Affiliation:
Department of Human Genetics, University of Newcastle upon Tyne, UK.
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MeSH Terms
Descriptor/Qualifier:
Alleles
Colombia
Ethnic Groups
HLA-DP Antigens / genetics*
Humans
Indians, South American / genetics*
Polymorphism, Genetic*
Chemical
Reg. No./Substance:
0/HLA-DP Antigens; 0/HLA-DPB1

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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