| HLA-B27 frequency in a group of patients with psoriatic arthritis. | |
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MedLine Citation:
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PMID: 23197202 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: HLA-B27 is associated with spondyloarthritis, a group of diseases that includes psoriatic arthritis. OBJECTIVES: To describe the HLA-B27 frequency in a group of Brazilian patients with psoriatic arthritis and correlate its presence or absence with their clinical manifestations. METHODS: Cross-sectional study with 44 psoriatic arthritis patients of a Rheumatology clinic. Demographic and social data were recorded, as were skin and joints clinical examination. HLA-B27 was tested. All data were processed descriptively and comparatively by appropriate software. Parametric and non parametric tests were used with 5% statistical significance. RESULTS: HLA-B27 was negative in 32 of the 44 patients (72,7%). Most of them were male, Caucasian, living in Rio de Janeiro, with plaque type psoriasis and average age of 52,9 years. There was statistical significant correlation between positive HLA-B27 and male gender (p=0,004). Negative HLA-B27 had a tendency to correlate with hands and wrists arthritis (p=0,07). There was an inverse significant correlation between HLA values and Schöber's test (p=0,02). CONCLUSION: Although HLA-B27 is negative in most of patients, it is significantly associated to male gender and inversely correlated with Schöber's test. |
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Authors:
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Danilo Garcia Ruiz; Mário Newton Leitão de Azevedo; Omar Lupi |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Anais brasileiros de dermatologia Volume: 87 ISSN: 1806-4841 ISO Abbreviation: An Bras Dermatol Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-11-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0067662 Medline TA: An Bras Dermatol Country: Brazil |
Other Details:
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Languages: eng Pagination: 847-50 Citation Subset: IM |
Affiliation:
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Federal University of Rio de Janeiro. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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