| HLA-B27 associated spondyloarthropathy, vasculitis, and amyloid enteropathy: response to infliximab. | |
| | |
MedLine Citation:
|
PMID: 15693105 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
In 2000 we described a patient with HLA-B27 associated spondyloarthropathy (SpA) and severe ascending aortitis requiring surgical intervention. Despite continued immunosuppressive therapy she developed narrowing of the distal part of the right subclavian artery and proximal axillary artery secondary to active vasculitis. In addition, biopsy-proven amyloid gastroenteropathy developed causing persistent diarrhea and iron deficiency anemia. Treatment with infliximab resulted in resolution of joint symptoms and rapid improvement in laboratory markers of inflammation. Diarrhea settled more gradually, such that her bowel habit had normalized 16 months after therapy commenced. |
| | |
Authors:
|
Lisa K Stamp; John L O'Donnell |
Related Documents
:
|
678095 - Surgical treatment of the thoracic outlet compression syndrome. 901185 - Coronary-subclavian steal. 21187695 - Detection of pulmonary embolism with 99mtc-labeled f(ab)2 fragment of anti-p-selectin m... 16096825 - Mri diagnosis of isolated origin of the left subclavian artery from the left pulmonary ... 19770605 - Intra-arterial injection in the rat brain: evaluation of steroids used for transforamin... 10359265 - Reverse flow instep island flap. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: The Journal of rheumatology Volume: 32 ISSN: 0315-162X ISO Abbreviation: J. Rheumatol. Publication Date: 2005 Feb |
Date Detail:
|
Created Date: 2005-02-04 Completed Date: 2005-04-28 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7501984 Medline TA: J Rheumatol Country: Canada |
Other Details:
|
Languages: eng Pagination: 382-5 Citation Subset: IM |
Affiliation:
|
Department of Medicine and Health Sciences, Christchurch School of Medicine, Otago University, Christchurch, New Zealand. lisa.stamp@cdhb.govt.nz |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Amyloidosis / drug therapy, immunology*, pathology Antibodies, Monoclonal / therapeutic use* Antirheumatic Agents / therapeutic use* Aortitis / drug therapy, immunology*, pathology Drug Therapy, Combination Female Gastroenteritis / drug therapy, immunology*, pathology HLA-B27 Antigen / immunology* Humans Methotrexate / therapeutic use Prednisone / therapeutic use Spondylarthropathies / drug therapy, immunology*, pathology Treatment Outcome |
| Chemical | |
Reg. No./Substance:
|
0/Antibodies, Monoclonal; 0/Antirheumatic Agents; 0/HLA-B27 Antigen; 0/infliximab; 53-03-2/Prednisone; 59-05-2/Methotrexate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bilateral ocular myositis as a late complication of dermatomyositis.
Next Document: Acute pancreatitis with pseudocyst formation in a patient with polyarteritis nodosa.