Document Detail

Is HLA B27 antigen a predictor of cardiac or pulmonary disease in patients with rheumatoid arthritis?
MedLine Citation:
PMID:  2068538     Owner:  NLM     Status:  MEDLINE    
Pericarditis was a frequent echocardiographic finding in 20 HLA B27 positive patients with erosive, seropositive rheumatoid arthritis (RA) and in 20 B27 negative RA controls (35% and 30% respectively). There was no significant difference in echocardiographic 2-D or M-mode measurements between the groups. A 48 hour continuous electrocardiographic monitoring, showed that ventricular extrasystoles were more frequent (p less than 0.01) in the B27 negative patients. Pulmonary diffusion capacity was reduced in 25% of the patients in both groups. There were no association between clinical or laboratory data and the cardiac or pulmonary findings except for the finding of a higher frequency of treatment with corticosteroids in patients with pericarditis.
S Rantapää Dahlqvist; C Backman; P Bjerle; O Johnson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of rheumatology     Volume:  20     ISSN:  0300-9742     ISO Abbreviation:  Scand. J. Rheumatol.     Publication Date:  1991  
Date Detail:
Created Date:  1991-08-13     Completed Date:  1991-08-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0321213     Medline TA:  Scand J Rheumatol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  165-71     Citation Subset:  IM    
Department of Rheumatology, University Hospital, Umeå, Sweden.
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MeSH Terms
Arthritis, Rheumatoid / complications*,  immunology
HLA-B27 Antigen / analysis*
Heart Diseases / diagnosis,  etiology*
Lung Diseases / diagnosis,  etiology*
Monitoring, Physiologic
Reg. No./Substance:
0/HLA-B27 Antigen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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