| HIV testing and antiretroviral treatment strategies for prevention of HIV infection: impact on antiretroviral drug resistance. | |
| | |
MedLine Citation:
|
PMID: 21929723 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
"Test and treat" is a strategy in which widespread screening for human immunodeficiency virus (HIV) is followed by immediate antiretroviral therapy for those testing positive, thereby potentially reducing infectiousness in larger cohorts of infected patients. However, there is a concern that test and treat could lead to increased levels of transmissible drug-resistant HIV, especially if viral load and/or drug resistance is not routinely monitored. Reviews of the existing literature show that up to now, even in the absence of laboratory tests, drug resistance has not created major problems in sub-Saharan Africa. Here we discuss the current evidence for the effectiveness of a preventive test and treat approach and the challenges and implications for daily clinical practice and public health. |
| | |
Authors:
|
Brooke E Nichols; Charles A B Boucher; David A M C van de Vijver |
Related Documents
:
|
21731593 - Spiritual well-being and health-related quality of life among african-american women wi... 21975433 - Chronic viral hepatitis and risk of lymphoid malignancies: a retrospective twelve-year ... 11589433 - The evidence for rickettsial disease arising in new zealand. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-9-19 |
Journal Detail:
|
Title: Journal of internal medicine Volume: - ISSN: 1365-2796 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
|
Created Date: 2011-9-20 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8904841 Medline TA: J Intern Med Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 The Association for the Publication of the Journal of Internal Medicine. |
Affiliation:
|
Department of Virology, Erasmus Medical Centre, Erasmus University, Rotterdam, The Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Looking for reference genes for real-time quantitative PCR experiments in Rhodnius prolixus (Hemipte...
Next Document: Dual localization of glutathione S-transferase in the cytosol and mitochondria: implications in oxid...