| HIV infection of non-dividing cells: a divisive problem. | |
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MedLine Citation:
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PMID: 17067381 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Understanding how lentiviruses can infect terminally differentiated, non-dividing cells has proven a very complex and controversial problem. It is, however, a problem worth investigating, for it is central to HIV-1 transmission and AIDS pathogenesis. Here I shall attempt to summarise what is our current understanding for HIV-1 infection of non-dividing cells. In some cases I shall also attempt to make sense of controversies in the field and advance one or two modest proposals. |
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Authors:
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Ariberto Fassati |
Publication Detail:
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Type: Journal Article Date: 2006-10-26 |
Journal Detail:
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Title: Retrovirology Volume: 3 ISSN: 1742-4690 ISO Abbreviation: Retrovirology Publication Date: 2006 |
Date Detail:
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Created Date: 2006-11-08 Completed Date: 2006-11-22 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 101216893 Medline TA: Retrovirology Country: England |
Other Details:
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Languages: eng Pagination: 74 Citation Subset: IM |
Affiliation:
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Wohl Virion Centre and MRC-UCL Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, 46 Cleveland Street, London W1T 4JF, UK. a.fassati@ucl.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Active Transport, Cell Nucleus Animals Capsid / metabolism Cell Nucleus / metabolism, virology* HIV Reverse Transcriptase / metabolism HIV-1 / pathogenicity, physiology* Humans Interphase Nucleoproteins / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Nucleoproteins; EC 2.7.7.49/HIV Reverse Transcriptase |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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