Document Detail


HHV-8-related visceral Kaposi's sarcoma following allogeneic HSCT: Report of a pediatric case and literature review.
MedLine Citation:
PMID:  20345616     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Sala I, Faraci M, Magnano GM, Sementa A, di Marco E, Garaventa A, Micalizzi C, Lanino E, Morreale G, Moroni C, Castagnola E. HHV-8-related visceral Kaposi's sarcoma following allogeneic HSCT: Report of a pediatric case and literature review. Pediatr Transplantation 2011: 15:E8-E11. © 2010 John Wiley & Sons A/S. Abstract:  An HHV-8-related visceral KS was diagnosed in a 10-yr-old boy after partially matched allogeneic HSCT. This complication occurred 463 days after HSCT and involved tonsils, lymph nodes, hard palate, lung, skin, and paranasal sinuses. Treatment with pegylated liposomal doxorubicin induced long-term remission (33 months) of this disease. HHV-8 infection is quite frequent after HSCT, but KS, and especially its visceral form, is a very rare complication, and its association with HHV-8 has been documented even less frequently. However, our observation suggests that HHV-8-related KS should be taken into consideration in the differential diagnosis of late post-HSCT complications.
Authors:
Ilaria Sala; Maura Faraci; Gian M Magnano; Angela Sementa; Eddi di Marco; Alberto Garaventa; Concetta Micalizzi; Edoardo Lanino; Giuseppe Morreale; Cristina Moroni; Elio Castagnola
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric transplantation     Volume:  15     ISSN:  1399-3046     ISO Abbreviation:  Pediatr Transplant     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9802574     Medline TA:  Pediatr Transplant     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  E8-E11     Citation Subset:  IM    
Copyright Information:
© 2010 John Wiley & Sons A/S.
Affiliation:
Department of Hematology-Oncology, Infectious Diseases Unit Department of Hematology-Oncology, Hemopoietic Stem Cell Transplant Unit Radiology Service Pathology Service Central Laboratory Analysis Unit, Experimental-Clinical Medicine Laboratory Department of Hematology-Oncology, Oncology Unit Department of Hematology-Oncology, Hematology Unit, G. Gaslini Children's Research Institute, Genova, Italy.
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