Document Detail

HEMA reactivity with demineralized dentin.
MedLine Citation:
PMID:  20036305     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: 2-Hydroxyethylmethacrylate (HEMA) was compared to its epoxy analogue, glycidoxypropylmethacrylate (GMA), for reactivity with 2,6-diaminohexanoic acid (Lysine), an amino acid present in collagen possessing a reactive amino side chain. The aim was to verify whether HEMA could chemically react with collagen fibers. METHODS: Capillary electrophoresis was used to analyse reaction products together with computer aided chemistry. Retention of HEMA in demineralized dentine particles was investigated by infrared spectroscopy. RESULTS: It was found by that HEMA does not form any new molecular species when contacted with lysine whereas GMA completely reacts to form the expected addition product. Computer aided chemistry confirmed this finding. Infrared spectroscopy showed that demineralized dentin has strong affinity for HEMA and retains this monomer despite extensive water washing. CONCLUSIONS: We interpret this behavior as demonstrating solvation of HEMA in the collagen polymer network.
Patrick Sharrock; Genevi?ve Gr?goire
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-12-28
Journal Detail:
Title:  Journal of dentistry     Volume:  38     ISSN:  1879-176X     ISO Abbreviation:  J Dent     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-09     Completed Date:  2010-06-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0354422     Medline TA:  J Dent     Country:  England    
Other Details:
Languages:  eng     Pagination:  331-5     Citation Subset:  D; IM    
Copyright Information:
Copyright 2010 Elsevier Ltd. All rights reserved.
Medical and Spatial Imaging Laboratory, University Toulouse III, Toulouse, France.
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MeSH Terms
Acid Etching, Dental*
Collagen / chemistry
Dental Materials / chemistry*
Dentin / chemistry*
Electrophoresis, Capillary
Epoxy Compounds / chemistry
Lysine / chemistry
Materials Testing
Methacrylates / chemistry*
Molecular Structure
Spectrophotometry, Infrared
Time Factors
Reg. No./Substance:
0/Dental Materials; 0/Epoxy Compounds; 0/Methacrylates; 106-91-2/glycidyl methacrylate; 56-87-1/Lysine; 868-77-9/hydroxyethyl methacrylate; 9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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