Document Detail


HELP LDL-apheresis in two cases of familial hypercholesterolemic pregnant women.
MedLine Citation:
PMID:  21257349     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We report our experience with selective LDL-apheresis in two women affected by autosomal recessive hypercholesterolemia and heterozygous familial hypercholesterolemia respectively, during pregnancy. To date only a few cases have been reported, because of the rarity of pregnancy in these patients and a hesitation of physicians to perform extracorporeal treatment. One of the patients had severe coronary artery disease, an absolute contraindication for pregnancy. Both patients had extremely elevated lipoprotein values because of their primary dyslipidemia, pregnancy-related modification of their lipid profile, and mandatory discontinuation of lipid-lowering drugs. In both cases the use of the Heparin-induced Extracorporeal Lipoprotein Precipitation (HELP) therapy improved the clinical situation and resulted in a good outcome for both mother and fetus.
Authors:
Sandra Anedda; Silvia Mura; Costantino Marcello; Paolo Pintus
Related Documents :
10625209 - Detection of decreased response to activated protein c during pregnancy by an endogenou...
10561629 - Presentation of venous thromboembolism during pregnancy.
22645279 - Birth weight following pregnancy during the 2003 southern california wildfires.
8994239 - Venous thromboembolism during pregnancy: a current review of diagnosis and management.
19474699 - Risk factors for clinical manifestations in carriers of factor v leiden and prothrombin...
15188139 - Placental pathology in fetal thrombophilia.
16532909 - Obstetricians' attitudes and opinions on sickness absence and benefits during pregnancy.
10735049 - Postnatal health and welfare of offspring conceived in vitro: a case for epidemiologica...
552769 - The treatment with 2-brom-alfa ergocriptine in the syndrome amenorrhea-galactorrhea.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-21
Journal Detail:
Title:  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis     Volume:  -     ISSN:  1473-0502     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-1-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101095653     Medline TA:  Transfus Apher Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Center for Metabolic Diseases and Atherosclerosis - Az. Ospedaliera "G. Brotzu" - Cagliari, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Understanding the laminated layer of larval Echinococcus I: structure.
Next Document:  DNA-based methods in the immunohematology reference laboratory.