| HELLP Syndrome with and without Eclampsia. | |
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MedLine Citation:
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PMID: 20827656 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We assessed pregnancy outcomes for patients with HELLP syndrome (hemolysis; elevated liver enzymes; low platelet count) with and without concurrent eclampsia. We performed a retrospective investigation of data spanning three decades of patients with class 1 or 2 HELLP syndrome with concurrent eclampsia (HELLP + E) and patients with HELLP syndrome without eclampsia. Data were analyzed by appropriate tests for continuous or categorical outcomes with differences considered significant if P < 0.05. During 1981 to 1996 and 2000 to 2006, there were 693 patients with class 1 or 2 HELLP syndrome; altogether, 70 patients had HELLP + E. The only demographic difference was greater nulliparity in HELLP + E patients. Otherwise, inconsistent and clinically insignificant differences were observed between groups. Despite the relatively large size of the study groups, we were unable to detect a significant worsening of maternal or perinatal outcome in HELLP + E patients compared with HELLP patients. In our experience, eclampsia does not appear to contribute a significant adverse impact upon the course or outcome of HELLP syndrome pregnancies. |
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Authors:
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Sharon D Keiser; Michelle Y Owens; Marc R Parrish; Julie L Cushman; Laura Bufkin; Warren L May; James N Martin |
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Publication Detail:
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Type: Journal Article Date: 2010-09-08 |
Journal Detail:
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Title: American journal of perinatology Volume: 28 ISSN: 1098-8785 ISO Abbreviation: Am J Perinatol Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-03-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8405212 Medline TA: Am J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 187-94 Citation Subset: IM |
Copyright Information:
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© Thieme Medical Publishers. |
Affiliation:
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Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Winfred L. Wiser Hospital for Women and Infants, and the Biostatistics Center, University of Mississippi Medical Center, Jackson, Mississippi. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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