Document Detail


HDAC3 at the fulcrum of an epithelial-mesenchymal balance.
MedLine Citation:
PMID:  21884971     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
In this issue of Molecular Cell, Wu et al. (2011) reveal an essential role for a chromatin modifier, histone deacetylase 3 (HDAC3), in hypoxia-induced epithelial-mesenchymal transition (EMT); HIF-activated HDAC3 integrates with WDR5 to impose chromatin modifications that culminate in EMT.
Authors:
Sendurai A Mani; Michelle Craig Barton
Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Molecular cell     Volume:  43     ISSN:  1097-4164     ISO Abbreviation:  Mol. Cell     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-09-02     Completed Date:  2011-12-22     Revised Date:  2013-02-20    
Medline Journal Info:
Nlm Unique ID:  9802571     Medline TA:  Mol Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  697-8     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Department of Molecular Pathology, The Center for Stem Cell and Developmental Biology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. smani@mdanderson.org
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Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
R01 DK078024/DK/NIDDK NIH HHS
Comments/Corrections
Comment On:
Mol Cell. 2011 Sep 2;43(5):811-22   [PMID:  21884981 ]

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