Document Detail

HACEK endocarditis in infants and children: two cases and a literature review.
MedLine Citation:
PMID:  12799515     Owner:  NLM     Status:  MEDLINE    
We report 2 cases of Haemophilus parainfluenzae endocarditis and review 34 cases of HACEK endocarditis from the literature. HACEK organisms are the most common cause of Gram-negative endocarditis in children. They have a propensity to form friable vegetations (especially H. parainfluenzae) that break off and cause symptomatic emboli. HACEK endocarditis (from a review of the 36 published cases) may involve previously normal hearts (33%), may be complicated by embolization (31%) and may require vegetectomy or other surgery (31%). Mortality with HACEK endocarditis was 14%. HACEK organisms may be resistant to penicillins but are susceptible to third generation cephalosporins.
Henry M Feder; Jenna C Roberts; Juan C Salazar; Harris B Leopold; Olga Toro-Salazar
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  22     ISSN:  0891-3668     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-06-11     Completed Date:  2003-07-25     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  557-62     Citation Subset:  IM    
Division of Infectious Disease, Connecticut Children's Medical Center, Hartford, CT, USA.
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MeSH Terms
Ceftriaxone / administration & dosage*
Endocarditis, Bacterial / drug therapy*,  microbiology*,  mortality
Follow-Up Studies
Haemophilus / classification*
Haemophilus Infections / diagnosis*,  drug therapy*,  mortality
Risk Assessment
Severity of Illness Index
Survival Rate
Treatment Outcome
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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