| H2-receptors and traumatic oedema. | |
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MedLine Citation:
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PMID: 722401 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of the H2-antagonists, metiamide and cimetidine, on the oedema following limb ischaemia or scald have been investigated in two strains of rat. No inhibition of oedema formation was found except when large doses of cimetidine were given before scalding. This effect was attributed to the fall in body temperature. Our results do not support the view that H2-receptors are concerned in the vascular response to injury. |
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Authors:
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R A Little; J Savic; H B Stoner |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of pathology Volume: 125 ISSN: 0022-3417 ISO Abbreviation: J. Pathol. Publication Date: 1978 Aug |
Date Detail:
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Created Date: 1979-02-26 Completed Date: 1979-02-26 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0204634 Medline TA: J Pathol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 201-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Temperature / drug effects Burns / complications Cimetidine / pharmacology, therapeutic use* Depression, Chemical Edema / etiology, physiopathology, prevention & control* Guanidines / therapeutic use* Male Metiamide / therapeutic use* Rats Receptors, Histamine H2 / drug effects Thiourea / analogs & derivatives* |
| Chemical | |
Reg. No./Substance:
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0/Guanidines; 0/Receptors, Histamine H2; 34839-70-8/Metiamide; 51481-61-9/Cimetidine; 62-56-6/Thiourea |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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