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H(2) O(2) - and pH-sensitive CdTe quantum dots as fluorescence probes for the detection of glucose.
MedLine Citation:
PMID:  22941960     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A novel fluorescence assay system for glucose was developed with thioglycollic acid (TGA)-capped CdTe quantum dots (QDs) as probes. The luminescence quantum yield of the TGA-capped CdTe QDs was highly sensitive to H(2) O(2) and pH. In the presence of glucose oxidase, glucose is oxidized to yield, gluconic acid and H(2) O(2) . H(2) O(2) and H(+) (dissociated from gluconic acid) intensively quenched the fluorescence of QDs. The experimental results showed that the quenched fluorescence was proportional to the glucose concentration within the range of 0.01-5.0 mm under optimized experimental conditions. Compared with most of the existing methods, this newly developed system possesses many advantages, including simplicity, low cost, high flexibility, and good sensitivity. Furthermore, no complicated chemical modification of QDs and enzyme immobilization was needed in this system. Copyright © 2012 John Wiley & Sons, Ltd.
Authors:
Yinping Li; Baoxin Li; Junli Zhang
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-3
Journal Detail:
Title:  Luminescence : the journal of biological and chemical luminescence     Volume:  -     ISSN:  1522-7243     ISO Abbreviation:  Luminescence     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100889025     Medline TA:  Luminescence     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 John Wiley & Sons, Ltd.
Affiliation:
Key laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Xi'an, 710062, China.
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