Document Detail


Gynecologic disorders and menstrual cycle lightheadedness in postural tachycardia syndrome.
MedLine Citation:
PMID:  22721633     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess differences in gynecologic history and lightheadedness during menstrual cycle phases among patients with POTS and healthy control women.
METHODS: In a prospective, questionnaire-based study carried out at Paden Autonomic Dysfunction Center, Vanderbilt University, between April 2005 and January 2009, a custom-designed questionnaire was administered to patients with POTS (n=65) and healthy individuals (n=95). The results were analyzed via Fisher exact test and Mann-Whitney U test.
RESULTS: Patients with POTS reported increased lightheadedness through all phases of the menstrual cycle phases as compared with healthy controls. Both groups experienced the greatest lightheadedness during menses, and a decrease in lightheadedness during the follicular phase. Patients with POTS reported a higher incidence of gynecologic diseases as compared with healthy controls.
CONCLUSION: The severity of lightheadedness was found to vary during the menstrual cycle, which may relate to changes in estrogen levels. Patients with POTS also reported an increase in estrogen-related gynecologic disease.
Authors:
Kiffany J Peggs; Hovan Nguyen; Diba Enayat; Nancy R Keller; Ayman Al-Hendy; Satish R Raj
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2012-06-20
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  118     ISSN:  1879-3479     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-07     Completed Date:  2013-01-17     Revised Date:  2013-09-03    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  242-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Paden Autonomic Dysfunction Service, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Dizziness / etiology*
Female
Genital Diseases, Female / complications*
Humans
Menstrual Cycle*
Middle Aged
Postural Orthostatic Tachycardia Syndrome / complications*
Prospective Studies
Questionnaires
Severity of Illness Index
Young Adult
Grant Support
ID/Acronym/Agency:
1 UL1 RR024975/RR/NCRR NIH HHS; K23 RR020783/RR/NCRR NIH HHS; KL2 RR024977/RR/NCRR NIH HHS; KL2 TR000446/TR/NCATS NIH HHS; M01 RR000095/RR/NCRR NIH HHS; P01 HL056693/HL/NHLBI NIH HHS; P01 HL56693/HL/NHLBI NIH HHS; R01 HD 046228/HD/NICHD NIH HHS; R01 HL071784/HL/NHLBI NIH HHS; R01 HL102387/HL/NHLBI NIH HHS; R01 HL102387/HL/NHLBI NIH HHS; R01 NS055670/NS/NINDS NIH HHS; TL1 RR024978/RR/NCRR NIH HHS; TL1 TR000447/TR/NCATS NIH HHS; UL1 RR024975/RR/NCRR NIH HHS; UL1 TR000445/TR/NCATS NIH HHS
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