Document Detail

Gynaecological cancers in pregnancy.
MedLine Citation:
PMID:  22325661     Owner:  NLM     Status:  MEDLINE    
Cervical and ovarian cancers are the most common gynaecological cancers diagnosed during pregnancy. In early-stage cervical cancer during the first and at the beginning of the second trimester, the two main considerations for management of the patient are the tumour size (and stage) and nodal staging. MRI and laparoscopic lymphadenectomy are useful for clinicians planning a potentially conservative approach. The management of patients with locally advanced cervical disease is controversial and should be discussed on a case-by-case basis according to the tumour size, radiological findings, the term of pregnancy, and the patient's wishes. Different histological types of malignant ovarian diseases arise during pregnancy and their management depends on the diagnosis (histological subtypes, tumour differentiation, and nodal status), the tumour stage, and the trimester of the pregnancy. In patients with peritoneal spread or high-risk early-stage disease, neoadjuvant chemotherapy with pregnancy preservation could be appropriate.
Philippe Morice; Catherine Uzan; Sebastien Gouy; Claire Verschraegen; Christine Haie-Meder
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Lancet     Volume:  379     ISSN:  1474-547X     ISO Abbreviation:  Lancet     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-02-13     Completed Date:  2012-02-21     Revised Date:  2012-05-29    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  England    
Other Details:
Languages:  eng     Pagination:  558-69     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Department of Gynecologic Surgery, Institut Gustave Roussy, Villejuif, France.
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MeSH Terms
Fetal Development
Ovarian Neoplasms / diagnosis,  therapy*
Practice Guidelines as Topic
Pregnancy Complications, Neoplastic / diagnosis,  therapy*
Uterine Cervical Neoplasms / diagnosis,  therapy*
Comment In:
Lancet. 2012 May 26;379(9830):1948; author reply 1949   [PMID:  22633029 ]
Lancet. 2012 May 26;379(9830):1949; author reply 1949-50   [PMID:  22633030 ]

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