Document Detail

Gut microbiota and probiotics in maternal and infant health.
MedLine Citation:
PMID:  21543533     Owner:  NLM     Status:  Publisher    
The interplay between both heredity and environmental factors seems to affect every stage of development from conception to the early postnatal period with potential long-term effects on child and adult health. During pregnancy, immune and metabolic functions of the fetus are dependent on the mother; moreover, the refinement of these functions seems to commence inside the uterus and to be diet sensitive. The microbiota inhabiting the intestinal tract develop an array of physiologic roles within the human body, which influences both metabolic and immune functions, particularly during early neonatal life and possibly even in utero. Transmission of bacteria from the mother to the neonate through direct contact with maternal microbiota during birth and through breast milk during lactation also seems to influence the infant's gut colonization, with potential health consequences. In this context, intentional modulation of microbiota composition through the use of probiotics during the perinatal and early postnatal period has been proposed as a possible dietary strategy to reduce risk of disease. Herein, studies are reviewed on the composition of the intestinal microbiota during pregnancy and clinical trials evaluating the effects of perinatal administration of probiotics on different clinical outcomes.
Yolanda Sanz
Related Documents :
474753 - Maternal starvation and progesterone secretion, litter size, and growth in the pig.
21389673 - Splenic circumference at midpregnancy as a predictor of hemoglobin bart's disease among...
9057543 - Predicting poor neonatal outcome: a comparative study of noninvasive antenatal testing ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-4
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  -     ISSN:  1938-3207     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Microbial Ecophysiology and Nutrition Research Group, Institute of Agrochemistry and Food Technology, Spanish National Research Council, Valencia, Spain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Fetal regulation of iron transport during pregnancy.
Next Document:  How can the Developmental Origins of Health and Disease (DOHaD) hypothesis contribute to improving h...