Document Detail


Gustatory hedonic value: potential function for forebrain control of brainstem taste processing.
MedLine Citation:
PMID:  18675299     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Among well-nourished populations, eating beyond homeostatic needs when presented with caloric-dense palatable food evidences the assertion that an increasing proportion of consumption is driven by pleasure, not just by the need for calories. This presents a major health crisis because the affective component of foods constitutes a behavioral risk factor that promotes over consumption [Sorensen, L.B., Moller, P., Flint, A., Martens, M., Raben, A., 2003. Effect of sensory perception of foods on appetite and food intake: a review of studies on humans. Int. J. Obes. Relat. Metab. Disord. 27, 1152-1166; Yeomans, M.R., Blundell, J.E., Leshem, M., 2004. Palatability: response to nutritional need or need-free stimulation of appetite? Br. J. Nutr. 92 (Suppl. 1), S3-S14]. Overweight or obese individuals have an increased risk of developing hypertension, stroke, heart disease, chronic musculoskeletal problems, type-2 diabetes, and certain types of cancers [Hill, J.O., Catenacci, V., Wyatt, H.R., 2005. Obesity: overview of an epidemic. Psychiatr. Clin. N. Am. 28, 1-23, vii]. The etiology of obesity is complex involving genetic, metabolic, and behavioral factors, but ultimately results from long-term energy imbalance. Evidence indicates that learned and some forms of unlearned control of ingestive behavior driven by palatability (i.e. hedonic value) are critically dependent on reciprocal interactions between brainstem gustatory nuclei and the ventral forebrain. This review discusses the current understanding of centrifugal control of taste processing in subcortical gustatory nuclei and the potential role of such modulation in hedonic responding.
Authors:
Robert F Lundy
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-07-15
Journal Detail:
Title:  Neuroscience and biobehavioral reviews     Volume:  32     ISSN:  0149-7634     ISO Abbreviation:  Neurosci Biobehav Rev     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-22     Completed Date:  2009-02-03     Revised Date:  2011-09-26    
Medline Journal Info:
Nlm Unique ID:  7806090     Medline TA:  Neurosci Biobehav Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1601-6     Citation Subset:  IM    
Affiliation:
University of Louisville School of Medicine, Department of Anatomical Sciences and Neurobiology, 500 South Preston Street, Louisville, KY 40292, United States. robert.lundy@louisville.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Appetite / physiology
Brain Chemistry
Brain Stem / physiology*
Food Preferences*
Humans
Prosencephalon / physiology*
Taste / physiology*
Grant Support
ID/Acronym/Agency:
R01 DC006698-05/DC/NIDCD NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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