| Guinea pig pancreatic polypeptide: structure and pancreatic content. | |
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MedLine Citation:
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PMID: 3575148 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Guinea pig (GP) pancreatic polypeptide (PP) has been purified from an acid-alcohol extract of 6 GP pancreata by a series of 3 HPLC steps. The sequence for GP PP as compared with that of beef and human is shown: (Sequence: see text). In a single GP pancreas weighing 2.4 g the total PP content was 1.0 nmol and the total glucagon content 61 nmol; in a single dog pancreas weighing 35 g the total PP was 385 nmol and the total glucagon 81 nmol. The relatively low content of PP in GP pancreas is consistent with the fact that the GP lacks a ventral pancreas, the region in which PP is found in highest concentration. The high glucagon content of GP pancreas is consistent with that reported in earlier studies. |
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Authors:
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J Eng; C G Huang; Y C Pan; J D Hulmes; R S Yalow |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Peptides Volume: 8 ISSN: 0196-9781 ISO Abbreviation: Peptides Publication Date: 1987 Jan-Feb |
Date Detail:
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Created Date: 1987-06-17 Completed Date: 1987-06-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8008690 Medline TA: Peptides Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 165-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acid Sequence Animals Cattle Chromatography, High Pressure Liquid Dogs Glucagon / analysis Guinea Pigs Pancreas / analysis* Pancreatic Polypeptide / isolation & purification* Radioimmunoassay |
| Chemical | |
Reg. No./Substance:
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59763-91-6/Pancreatic Polypeptide; 9007-92-5/Glucagon |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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