Document Detail

Guidelines on guidelines: focus on isolated systolic hypertension in youth.
MedLine Citation:
PMID:  23412425     Owner:  NLM     Status:  MEDLINE    
Current guidelines on isolated systolic hypertension (ISH) suggest the same treatment to patients of all ages. Application of these guidelines in youth with ISH may not be appropriate, as presently no data show adverse outcome or benefit of drug therapy in this group. Simple noninvasive tonometric techniques now enable physicians to measure the central aortic pressure waveform and amplification of the pressure pulse. ISH in youth is usually caused by high amplification of the central pressure wave, whereas ISH in the elderly (>age 60) is attributable to aortic stiffening. This is the only group with ISH shown to have an adverse prognosis and to warrant drug therapy.
Michael F O'Rourke; Audrey Adji
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Publication Detail:
Type:  Editorial    
Journal Detail:
Title:  Journal of hypertension     Volume:  31     ISSN:  1473-5598     ISO Abbreviation:  J. Hypertens.     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-07     Completed Date:  2013-08-29     Revised Date:  2013-11-18    
Medline Journal Info:
Nlm Unique ID:  8306882     Medline TA:  J Hypertens     Country:  England    
Other Details:
Languages:  eng     Pagination:  649-54     Citation Subset:  IM    
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MeSH Terms
Antihypertensive Agents / therapeutic use
Hypertension / drug therapy,  physiopathology*
Practice Guidelines as Topic*
Young Adult
Reg. No./Substance:
0/Antihypertensive Agents
Comment In:
J Hypertens. 2013 Apr;31(4):655-8   [PMID:  23466891 ]
J Hypertens. 2013 Sep;31(9):1913-4   [PMID:  24107670 ]
J Hypertens. 2013 Sep;31(9):1911-3   [PMID:  24107669 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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