| Guideline-discordant periprocedural interruptions in warfarin therapy. | |
| | |
MedLine Citation:
|
PMID: 21304096 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Periprocedural interruptions in warfarin therapy increase thromboembolic risks to patients and are not indicated for all procedures. We sought to determine the frequency and guideline concordance of periprocedural warfarin interruptions to inform a future educational intervention. METHODS AND RESULTS: In October and November of 2009, an anonymous postal survey was sent to all patients followed for more than 1 year by the University of Michigan Anticoagulation service. Patients were asked how many times in the prior year they were requested to interrupt warfarin therapy for a medical or dental procedure or test and the specific indication for the requested interruption in warfarin therapy. A total of 1686 of 2133 (79%) subjects responded. The mean age of respondents was 69 years (SD=14 years). The majority were men (56%) and white (93%). Atrial fibrillation was the most common indication for warfarin therapy (n=966, 57%). At least 1 request to interrupt warfarin therapy in the prior year was given by 819 of 1648 (50%) respondents, including 481 of the 947 (51%) respondents taking warfarin for atrial fibrillation. Forty-eight percent of requests to interrupt warfarin among all respondents and 50% of requests to interrupt warfarin among those taking warfarin, specifically for atrial fibrillation, were for indications not supported by guideline statements. CONCLUSIONS: Periprocedural requests to interrupt warfarin therapy are common and are often discordant with current guidelines. Educational interventions may decrease risk of periprocedural thromboembolic complications. |
| | |
Authors:
|
Lesli E Skolarus; Lewis B Morgenstern; James B Froehlich; Lynda D Lisabeth; Devin L Brown |
Related Documents
:
|
18794436 - Nasal-air conditioning in patients with chronic rhinosinusitis and nasal polyposis. 21225176 - Clinical, nutritional and spirometric evaluation of patients with cystic fibrosis after... 21479356 - Evidence for methotrexate as a useful treatment for steroid-dependent chronic urticaria. 21168096 - Postoperative anterior spondylodiscitis after posterior pedicle screw instrumentation. 16229356 - The influence of cigarette smoke inhalation on bone density. a radiographic study in rats. 11830806 - Arthroscopic repair of full-thickness tears of the rotator cuff: 2- to 14-year follow-up. |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2011-02-08 |
Journal Detail:
|
Title: Circulation. Cardiovascular quality and outcomes Volume: 4 ISSN: 1941-7705 ISO Abbreviation: Circ Cardiovasc Qual Outcomes Publication Date: 2011 Mar |
Date Detail:
|
Created Date: 2011-03-16 Completed Date: 2011-07-28 Revised Date: 2011-10-27 |
Medline Journal Info:
|
Nlm Unique ID: 101489148 Medline TA: Circ Cardiovasc Qual Outcomes Country: United States |
Other Details:
|
Languages: eng Pagination: 206-10 Citation Subset: IM |
Affiliation:
|
Stroke Program, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Anticoagulants / contraindications*, therapeutic use Atrial Fibrillation / drug therapy* Blood Loss, Surgical / prevention & control Data Collection Female Humans Male Middle Aged Oral Surgical Procedures Patient Compliance* Preoperative Care* Risk Factors Stroke / epidemiology Surgical Procedures, Operative Thromboembolism / epidemiology Warfarin / contraindications*, therapeutic use |
| Grant Support | |
ID/Acronym/Agency:
|
K23 NS051202/NS/NINDS NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Anticoagulants; 81-81-2/Warfarin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Racial differences in incident heart failure during antihypertensive therapy.
Next Document: Mortality implications of primary percutaneous coronary intervention treatment delays: insights from...