| Guideline: appropriate use of tigecycline. | |
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MedLine Citation:
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PMID: 20529440 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Tigecycline, the first of a new class of antibiotics, the glycylcyclines, was licensed in South Africa for the parenteral treatment of adult patients with complicated intra-abdominal infections (cIAIs) and complicated skin and soft-tissue infections (cSSTIs). METHODS: A multidisciplinary meeting representative of the Association of Surgeons of South Africa, the Critical Care Society of Southern Africa, the Federation of Infectious Diseases Societies of Southern Africa, the South African Thoracic Society and the Trauma Society of South Africa was held to draw up a national guideline for the appropriate use of tigecycline. Background information reviewed included randomised controlled trials, other relevant publications and local antibiotic susceptibility patterns. The initial document was drafted at the meeting. Subsequent drafts were circulated to members of the working group for modification. OUTPUT: The guideline addresses several important aspects of the new agent, summarising key clinical data and highlighting important considerations with the use of the drug. The recommendations in this guideline are based on currently available scientific evidence together with the consensus opinion of the authors. CONCLUSION: This statement was written out of concern regarding the widespread misuse of antibiotics. Its primary intention is to facilitate heterogeneous use of antibiotics as a component of antibiotic stewardship and to highlight the appropriate use of tigecycline in particular. |
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Authors:
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A J Brink; D Bizos; K D Boffard; C Feldman; D C Grolman; J Pretorius; G A Richards; M Senekal; E Steyn; N Welkovic; ; ; ; ; |
Publication Detail:
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Type: Journal Article; Practice Guideline; Research Support, Non-U.S. Gov't Date: 2010-06-01 |
Journal Detail:
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Title: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde Volume: 100 ISSN: 0256-9574 ISO Abbreviation: S. Afr. Med. J. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-10 Completed Date: 2010-09-14 Revised Date: 2010-09-21 |
Medline Journal Info:
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Nlm Unique ID: 0404520 Medline TA: S Afr Med J Country: South Africa |
Other Details:
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Languages: eng Pagination: 388-94 Citation Subset: IM |
Affiliation:
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Ampath National Laboratory Services. brinka@ampath.co.za |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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pharmacokinetics,
pharmacology,
therapeutic use* Clostridium difficile / drug effects Drug Resistance, Multiple, Bacterial / drug effects Enterobacteriaceae / drug effects Humans Microbial Sensitivity Tests Minocycline / analogs & derivatives*, pharmacokinetics, pharmacology, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/tigecycline; 10118-90-8/Minocycline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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