| Guided tissue regeneration-based root coverage with a platelet concentrate graft: a 3-year follow-up case series. | |
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MedLine Citation:
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PMID: 19563301 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: A platelet concentrate graft (PCG) was applied underneath the barrier membrane in guided tissue regeneration (GTR)-based root coverage procedures. The purpose of this case study was to assess the effectiveness of the technique and the long-term outcomes. METHODS: Thirty-seven Miller Class I or II recession defects in six patients were treated using the PCG and a collagen membrane covered by an advanced mucogingival flap. Clinical parameters, such as vertical gingival recession depth (VRD), clinical attachment level (CAL), probing depth (PD), and width of keratinized tissue (WKT), were recorded presurgery (at baseline [BL]) and at 6 and 36 months of follow-up. The Wilcoxon signed-rank test and the Mann-Whitney test were used to assess statistical significance (alpha = 0.05). RESULTS: Between BL and 6 months, there was a statistically significant reduction in VRD (from 2.81 +/- 0.88 mm to 0.30 +/- 0.48 mm) and PD (from 2.59 +/- 0.50 mm to 1.14 +/- 0.35 mm), as well as an improvement in CAL (from 5.41 +/- 0.86 mm to 1.43 +/- 0.66 mm). These results remained stable over the following 30 months. There was no statistically significant change in WKT during the initial 6 months; however, the increase in WKT was statistically significant at the 36-month follow-up. When comparing the healing between the maxillary and mandibular teeth at 6 months, the VRD reduction was statistically significantly greater in the maxillary teeth, but the difference was not statistically significant 30 months later. The average root coverage at 6 and 36 months was 89.86% +/- 15.85% and 85.86% +/- 18.16%, respectively, with complete root coverage in 24 (64.86%) and 21 (56.76%) of the 37 teeth. CONCLUSIONS: The GTR-based technique using PCG was effective in reducing gingival recession. The outcomes remained stable for 3 years. |
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Authors:
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Terrence J Griffin; Wai S Cheung |
Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Journal of periodontology Volume: 80 ISSN: 0022-3492 ISO Abbreviation: J. Periodontol. Publication Date: 2009 Jul |
Date Detail:
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Created Date: 2009-06-30 Completed Date: 2009-11-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8000345 Medline TA: J Periodontol Country: United States |
Other Details:
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Languages: eng Pagination: 1192-9 Citation Subset: D; IM |
Affiliation:
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Department of Periodontology, Tufts University School of Dental Medicine, Boston, MA, USA. terrence.griffin@tufts.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Absorbable Implants Biological Dressings Blood Platelets* Follow-Up Studies Gingiva / surgery Gingival Recession / surgery* Gingivoplasty / methods* Guided Tissue Regeneration, Periodontal / methods* Humans Membranes, Artificial Surgical Flaps* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Membranes, Artificial |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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